BrettMD's then and now comparison:
Pharmacotherapy for alcohol use disorders has made progress since 1942 when amphetamine, vitamins, and psychotherapy alone were determined to be woefully inadequate for the treatment of alcoholism.
JAMA Network | JAMA | THE CONDITIONED REFLEX TREATMENT OF CHRONIC ALCOHOLISM: VIII. A REVIEW OF SIX YEARS EXPERIENCE WITH THIS TREATMENT OF 1,526 PATIENTS http://jama.jamanetwork.com/article.aspx?articleid=257611
JAMA Network | JAMA | AMPHETAMINE IN CHRONIC ALCOHOLISM http://jama.jamanetwork.com/article.aspx?articleid=289190
To the Editor:— The reply which recently appeared in Queries and Minor Notes to a letter relative to the use of amphetamine (benzedrine) in the treatment of chronic alcoholism as recommended by Dr. Wilfred Bloomberg might easily give rise to a regrettable misunderstanding. Dr. Bloomberg made the suggestion only after long experience with the drug in other conditions, for he (with Prinzmetal) was the first to report its effectiveness in the treatment of narcolepsy. He has further, in preparation, a detailed study of the effects of large doses given over a period of three years to some of his early patients and a careful survey of all the cases in which ill effects are reported to have followed the use of the drug. This study has led him to the belief that its use under medical supervision is entirely justified when dealing with such serious diseases as narcolepsy.
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